Mike Kyle currently competes in the World Series of Fighting's Heavyweight division. He has also competed in the UFC, the WEC, Strikeforce, Pancrase, King of the Cage, and the IFC. He is the former King of the Cage Light Heavyweight Champion.

Kyle is from Boise, Idaho. He attended Nampa High School and was very good friends with the late Justin Eilers, who Kyle would actually end up fighting in his second fight for the UFC. Eilers and a friend who were both two grades ahead of Kyle, taught him jiu-jitsu techniques when he was a sophomore in high school. Kyle was also a talented football player, played fullback for Butte College in Chico, California and Eastern Oregon University. During his early mixed martial arts career he split time between fighting and playing football. He was invited to a spring camp for the San Francisco 49ers, but ultimately decided to focus on mixed martial arts.

Kyle made his professional debut on March 10, 2001 when he was 18 years old and won by TKO only 90 seconds into the fight. He then won his next two fights, also by punches before debuting in the King of the Cage promotion. Kyle made his King of the Cage debut in a fight for the King of the Cage Super Heavyweight Championship against then King of the Cage Super Heavyweight Champion Dan Bobish. Kyle, who then weighed 275 lbs. was outweighed by Bobish, who was 55 lbs. bigger than Kyle. Kyle was handed his first career loss after he submitted due to punches.

In his next KOTC bout, Kyle made his Heavyweight debut against future King of the Cage Heavyweight Champion Paul Buentello. Kyle lost after he was knocked out from punches.

In his next fight, Kyle made his debut in the WEC, and snapped his two-fight losing streak with a knockout win. The 4-2 Kyle then made his IFC debut and again won by strikes as his opponent tapped out due to punches. Kyle then won his next two fights, the later being his second fight for the WEC.

Kyle made his UFC debut against Wes Sims winning via KO at 4:59 of round 1. Sims took the fight on less than a week’s notice after Kyle's original opponent got injured. Kyle dominated the entire first round and knocked Sims out at 4:59.

Kyle then fought the late Justin Eilers in a Heavyweight bout. This was a significant match-up as Eilers was a friend of Kyle's who had actually introduced Kyle to the sport of mixed martial arts. Kyle lost the fight when he was knocked out from a punch 74 seconds into the first round.

He then fought former WEC Heavyweight Champion James Irvin at UFC 51: Super Saturday winning via knockout in the first round.

After leaving the UFC, Kyle had planned to fight in the Pride Fighting Championships in Japan. However, the plan fell through and in his next bout he fought in Japan's Pancrase where he defeated Japanese legend Tsuyoshi Kohsaka after executing a flying knee as Kohsaka went in for a takedown. Kyle won the fight via Technical Decision in round 3 after ringside doctors ruled Kohsaka unable to continue. Kyle had cut down from 245 lbs. to 230 lbs. for the fight.

He then fought against Devin Cole at WEC 18, and lost by TKO. This was Kyle's first defeat in the WEC.

He then signed with Strikeforce, making his debut against Krzysztof Soszynski in a Heavyweight bout at Strikeforce: Shamrock vs. Gracie. The fight was declared a technical draw after Soszynski was accidentally poked in the eye by Kyle. Kyle then fought Brian Olsen for the WEC Heavyweight Championship and was disqualified after he hit Olsen with illegal strikes, for which he was placed on the national suspension list, and given an 18-month ban.

The 9-6-1 Kyle then fought at Strikeforce: Shamrock vs. Le against former All-American wrestler Wayne Cole in a Heavyweight bout and lost after he was submitted from an armbar. Kyle then returned to the IFC and won his bout via knockout, and followed this up with another win, this time via unanimous decision, his first career decision win.

Kyle then returned to Strikeforce to fight Rafael Calvacante in a Light Heavyweight bout at Strikeforce: Lawler vs. Shields. Kyle picked up one of the biggest victories of his career, winning by knockout against the future Strikeforce Light Heavyweight Champion. This was also significant because it was Calvacante's first decisive loss, as his only other defeat was by disqualification against fellow Brazilian Marcio Cruz.

After his huge win over Calvacante, Kyle fought against Brazilian jiu-jitsu specialist Fabricio Werdum in a Heavyweight bout at Strikeforce: Carano vs. Cyborg in San Jose, California. He lost the bout via guillotine choke submission.

He then fought Jeremy Freitag at Xtreme MMA Australia 1 winning via TKO due to knees in the round three.

Kyle next signed with King of the Cage and fought against Travis Wiuff in a Heavyweight, initially winning by TKO in the second round. However, it was changed to a no contest decision after it was determined Kyle hit Wiuff after the bell.

In his second fight with King of the Cage he fought Jon Murphy and won via TKO at 4:53 of round two. He then fought Tony Lopez for the King of the Cage Light Heavyweight Title and won via split decision after a 5 round battle, becoming the King of the Cage Light Heavyweight Champion.

Kyle fought against Abongo Humphrey at Strikeforce Challengers: del Rosario vs. Mahe. Kyle won via submission in the second round.

Kyle fought against Steve Oliver at Xtreme MMA Australia 3 Kyle won via TKO due to punches in round one, winning the XMMA Light Heavyweight Championship.

Kyle stepped in on late notice to fight Antonio "Bigfoot" Silva at Strikeforce: Henderson vs. Babalu II in St. Louis, Missouri in a Heavyweight bout. Kyle knocked Silva down with a powerful right hand and delivered many shots on the ground but was unable to finish. Silva defeated Kyle via second round TKO. Kyle later revealed that he broke his hand during the fight.

Kyle fought Marcos Rogerio de Lima at Strikeforce World Grand Prix: Barnett vs. Kharitonov. Kyle won by unanimous decision, picking apart the younger fighter with boxing techniques.

Kyle next faced Rafael Cavalcante in a rematch at Strikeforce 40 in what would be a title eliminator match for the vacant Strikeforce Light Heavyweight Championship. Kyle lost the fight via guillotine choke in the first round. After the fight, Cavalcante tested positive for a banned substance and, as a result, the CSAC declared the fight a "no contest".

Kyle faced Gegard Mousasi at Strikeforce: Marquardt vs. Saffiedine in January, 2013. He lost via submission in the first round. Kyle said that he would retire following the loss.

He has since stated that he will not retire.

Kyle then had a rematch with Travis Wiuff and won via knockout only 21 seconds into the fight.

Kyle faced former UFC Heavyweight Champion Andrei Arlovski at WSOF 5 in September 2013. Although he knocked Arlovski down with right hands in the first and third round, he lost the fight via unanimous decision.

Kyle faced Anthony Johnson at WSOF 8 and lost via KO in the first round.

Kyle was expected to face Maxim Grishin at Fight Nights: Battle of Moscow 17 on September 30, 2014. However, Kyle pulled out of the bout due to injury, he was replaced with Trevor Prangley.

Kyle faced Evgeny Erokhin on December 20, 2014 at FEFoMP: Russia's MMA Supercup. He lost the fight via KO in the second round.